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Cross Reaction Table - Drug Check

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DrugCheck®	X Reactivity Status	Pharmaceutical Name	Brand Name	Drug Use
Amphetamines	Potential	Amantadine	Amantadine	Parkinsonism
Methamphetamines	Potential	Bupropion	Wellbutrin & Zyban	Antidepressant & Smoking cessation
	Potential	Chloroquine	Aralen	Treats Malaria
	Potential	Chlorpromazine	Thorazine, Largactil	Treatment for psychotic disorders
	Potential	Desipramine	Norpramin	Antidepressant
	Potential	Dextroamphetamine	Dexedrine	Used for Narcolepsy "sleep attacks"
	Potential	Ephedrine	Ephedra and Ma Huang	Amphetamines
	Potential	Fenfluramine	Fen Phen	Fen Phen Diet pill outlawed by FDA
	Potential	Labetalol	Labetalol	Blood Pressure
	Potential	Mexiletine	Mexitil	Cardiovascular - treatment for arrhythmia
	Potential	n-acetyl procainamide	Procainmide	Cardiovascular - treatment for arrhythmia
	Potential	Phentremine	Adipex/Obenix/Oby-Trim	Diet Pills
	Potential	Phenylephrine *	Neo-Synephrine	Nasal Congestion, Hypotension, Ophthalmic solution
	Potential
	Potential	Propranolol	Inderal	Cardiovascular-Hypertension, (beta blocker)
	Potential	Pseudoephedrine *	Claritin-D,Sudafed & etc	Nasal congestion
	Potential	Quinacrine	Atabrine, Mepacrine	Protozoal infection of the intestinal tract
	Potential	Ranitidine *	ZANTAC	Treatment for Heartburn & Duodenal ulcer
	Potential	Selegiline	Selegiline	Parkinson's Disease
	Potential	Trazodone	Desyrel, Desyrel Dividose	Antidepressant medication
	Potential	Tyramine *	Tyramine	Headaches/blood pressure
	Potential	* Tested and do not crossreact

	Product Insert	d-Methamphetamine
	Product Insert	d-Amphetamine
	Product Insert	Chloroquine	Aralen	Treats Malaria
	Product Insert	Deoxyephedrine
	Product Insert	Methylenedioxymethamphetamine MDMA	Ecstacy

Barbiturates	Potential	Phenytoin	Dilantin	Anticonvulsant - Treatment for epilepsey
	Potential	Primidone	Mysoline	Anticonvulsant - Treatment for epilepsey
	Product Insert	Secobarbital	Seconal	Sedative
	Product Insert	Alphenal
	Product Insert	Amobarbital		Short term treatment fo insominia
	Product Insert	Aprobarbital		Relieve anxiety/sleep
	Product Insert	Barbital		Induce unconsciousness
	Product Insert	Butabarbital		Short term trestment of insomunia
	Product Insert	Butalbital		Headaches
	Product Insert	Pentobarbital	Nembutal	Sedative
	Product Insert	Phenobarbital	Luminal, Donntal	Epilepsy

Benzodiazepines	Potential	Oxaprozin	Daypro	Nonsteroidal Anti-Inflammatory - for Arthritis
	Potential	Sertraline	Zoloft	SSRI - Treatment for depression
	Product Insert	Oxazepam	Serax	Anti-Anxiety
	Product Insert	Alprazolam	Xanax	Anti-Anxiety
	Product Insert	Bromazepam	Tenix	Anti-Anxiety
	Product Insert	Chlordiazepoxide	Libritabs, Librium	Anti-Anxiety
	Product Insert	Clobazam	Mystan	Epilepsy
	Product Insert	Clonazepam	Klonopin	Anti-Anxiety
	Product Insert	Diazepam	Valium	Treat for Anxiety, Epilepsy & Muscle relaxant
	Product Insert	Estazolam	Prosum	Sleeping pill/ Cousin to Valium
	Product Insert	Flunitrazepam	Rohypnol	Date Rape drug
	Product Insert	Lorazepam	Ativan	Anti-Anxiety
	Product Insert	Nitrazepam	Rhoxal	Relief of Insomnia
	Product Insert	Nordiazepam - Metabolite	Diazepam	Tranquilizer
	Product Insert	Temazepam	Restoril	Relief of Insomnia
	Product Insert	Triazolam	Halcion	Short term basis to assist sleep

Marijuana	Product Insert	Dronabinol	Marinol	Liquid THC, to increase appetite
	Potential	Efavirenz	Sustiva, (Stocrin - Europe)	Treatment for AIDS
	Potential	Hemp Seed Oil	Cannabis seed, Hemp oil	Food, cosmetics
	Potential	Pantoprazole	Protonix, Pantoloc	GERD
	Potential	NOTE These drugs may Xreact	Nexium, Prilisec, Prevacid	GERD

Cocaine	Potential	TAC Solution	TAC Solution	Topical Cocaine for pain
	Product Insert	Benzoylecgonine		Cocaine Toothache drops
	Product Insert	Cocaine
	Product Insert	Ecgonine		Cocaine metabolites
	Product Insert	Ecgonine Methyl Ester		Cocaine metabolites

Methadone	Product Insert	None

Opiates	Potential	Fluoroquinolones		Treat Bacterial infections
	Potential	Ofloxacin	Floxin	Bacterial infections
	Potential	Papaverine		Used for erectile dyfunction, treat ischemia
	Potential	Poppy Seeds		Seasoning for baked goods
	Potential	Rifampcin & Rifampin	Rimactane, Rifadin, Rofact	Antimicrobial, treatment for TB
	Product Insert	Morphine		Pain
	Product Insert	6-Acetylmorphine	Metabolite of Heroin
	Product Insert	Codeine		Pain
	Product Insert	Ethyl morphine		Pain
	Product Insert	Hydromorphone		Pain
	Product Insert	Hydrocodone		Pain

Oxycodone	Product Insert	Oxycodone	OxyContin/Percolone/Roxicodone	Moderate to Severe Pain
	Product Insert	Hydrocodone	Vicodin	Analgesic with acetaminophen
	Product Insert	Hydromorphone	Dilaudid	Pain management
	Product Insert	Oxymorphone	Numorphan	Treatment for moderate to severe pain
	Product Insert	Codeine	Codeine	Pain management / Cough medicine

Phencyclidine (PCP)	Potential	Dextromethorphan	Dextromethorphan	Cough Treatment
	Potential	Diphenhydramine	Benadryl	Allergies
	Potential	Thioridazine	Mellaril	Tranquilizer, for psychotic disorders
	Potential	Venlafaxine	Effexor	Antidepressant
	Product Insert	Phencyclidine	PCP
	Product Insert	Thienylcyclohexylpiperidine

Data assimilated from: Cone 1997;Cone & Preston1999; Fed Register 2004; Gourlay et al. 2004;
Heit Gourlay 2004; Med letter 2002; STL 2004; Samyn et al.1999; Schuckit 2000 Simpson et al. 1997; Strang 1999; Warner 2003; Wolff et al 1999; Wyeth Med Com. Letter 3/2004 (Protonix); Wyeth Med Com. Letter 5/2005 (Effexor)

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